As Vice President, in 2016, Joe Biden launched the Cancer Moonshot with the mission to accelerate the rate of progress against cancer. The Center for Translational Data Science (CTDS) has maintained involvement in two projects that received support as part of the Cancer Moonshot and have strategic importance for CTDS: the Genomic Data Commons and the Blood Profiling Atlas in Cancer (BloodPAC). Today, President Biden is reigniting the Cancer Moonshot with renewed White House leadership of this effort. President Biden announced new goals for the Cancer Moonshot: to reduce the death rate from cancer by at least 50 percent over the next 25 years and improve the experience of people and their families living with and surviving cancer—and, by doing these and more, to end cancer as we know it today.